Chemoembolization (TACE) is a minimally invasive cancer treatment that delivers chemotherapy drugs directly to a tumor while simultaneously blocking the blood supply to the tumor. This targeted approach is primarily used to treat liver cancer, allowing higher doses of chemotherapy to be delivered to the tumor without exposing the rest of the body to the drugs. In this guide, we explore how TACE works, its benefits, and the top hospitals in India offering this treatment.
What is Chemoembolization (TACE) Therapy?
Transarterial Chemoembolization (TACE) is a procedure that delivers high doses of chemotherapy directly into a tumor’s blood supply. It combines chemotherapy with embolization, a process that blocks the blood vessels supplying the tumor, which helps to starve the tumor of nutrients and oxygen while allowing the chemotherapy drugs to remain in the tumor for a longer period of time.
How Does Chemoembolization (TACE) Therapy Work?
The TACE procedure involves injecting a mixture of chemotherapy drugs and embolic agents through a catheter directly into the artery that supplies the tumor. This approach targets the cancerous area while minimizing damage to surrounding healthy tissue. By cutting off the tumor's blood supply, TACE enhances the effectiveness of chemotherapy and limits systemic exposure to the drugs.
Which Cancers Can Be Treated with TACE?
Chemoembolization is primarily used to treat liver cancer, especially hepatocellular carcinoma (HCC). It is also used in some cases of metastatic liver cancer, where cancer has spread from other organs to the liver. The therapy is particularly effective for patients who are not suitable candidates for surgery or other local treatments.
1. How Does Chemoembolization (TACE) Help in Liver Cancer?
Chemoembolization (TACE) helps treat liver cancer by delivering high doses of chemotherapy directly to the tumor, while blocking the blood supply that feeds the cancer cells. This dual action increases the effectiveness of the treatment while minimizing the exposure of the rest of the body to the chemotherapy drugs.
TACE is often used for patients who are not eligible for surgery or liver transplantation and helps to shrink tumors, slow their growth, and improve survival rates.
Side effects include post-embolization syndrome, such as pain, fever, and nausea.
Advantages of Chemoembolization Therapy
TACE offers several advantages over conventional chemotherapy and other liver cancer treatments:
- Targeted Therapy: TACE delivers chemotherapy directly to the tumor, reducing exposure to the rest of the body and minimizing side effects.
- Higher Drug Concentration: The drugs remain in the tumor longer, allowing higher doses to be used without increasing toxicity to the body.
- Non-Surgical: TACE is a minimally invasive procedure that does not require major surgery, allowing for a faster recovery.
Side Effects of Chemoembolization Therapy
While TACE is generally well-tolerated, it can cause some side effects, including:
- Fatigue
- Mild pain or discomfort at the injection site
- Nausea or vomiting
- Fever
These side effects are usually temporary and manageable. However, patients with underlying liver conditions may experience more severe side effects, such as liver dysfunction.
Eligibility for Chemoembolization Therapy
TACE is typically recommended for patients with liver cancer that cannot be treated with surgery or other local treatments, such as radiofrequency ablation. It is also used for patients whose tumors are confined to the liver and who have adequate liver function. A thorough evaluation, including imaging tests and liver function assessments, is necessary to determine eligibility.
How to Prepare for TACE Therapy in India
Before undergoing TACE, patients will undergo a series of tests, including imaging scans to assess the size and location of the tumor, as well as blood tests to evaluate liver function. It is important to follow all pre-procedure instructions provided by the oncologist to ensure the best possible outcome.
Top Hospitals Offering TACE Therapy in India
Several top hospitals in India offer TACE therapy for liver cancer patients. Leading institutions like Tata Memorial Hospital in Mumbai and Fortis Memorial Research Institute in Gurgaon provide advanced interventional radiology and oncology services, including TACE. Apollo Cancer Centres across India also offer this therapy as part of their comprehensive liver cancer treatment programs.
Cost of Chemoembolization (TACE) Therapy in India
The cost of TACE therapy in India ranges between ₹1.5 lakh and ₹4 lakh per treatment session, depending on the type of cancer, the hospital, and the specific treatment plan. This is significantly lower than the cost of TACE in Western countries, making India a popular destination for patients seeking affordable, high-quality cancer care.
Success Rates of Chemoembolization Therapy
Studies have shown that TACE can significantly improve survival rates in patients with liver cancer, particularly when combined with other treatments like immunotherapy or targeted therapy. While TACE is not a cure for liver cancer, it can help shrink tumors, relieve symptoms, and prolong survival in many patients.
Future of TACE Therapy in Cancer Treatment
Ongoing research is exploring ways to improve the effectiveness of TACE therapy, including combining it with newer treatments like immunotherapy and targeted drugs. Advances in imaging and catheter technology are also helping to make the procedure more precise and less invasive. As research progresses, TACE is expected to play an even larger role in liver cancer treatment.
Frequently Asked Questions (FAQs) About TACE Therapy in India
What is the cost of Chemoembolization (TACE) Therapy in India?
The cost of TACE therapy in India ranges from ₹1.5 lakh to ₹4 lakh per session, depending on the hospital and treatment plan.
Which cancers can be treated with TACE Therapy?
TACE is primarily used to treat liver cancers, including hepatocellular carcinoma (HCC) and metastatic liver cancer.
Is TACE a curative treatment?
TACE is not a curative treatment but is highly effective in controlling tumor growth and prolonging survival in liver cancer patients.
How many sessions of TACE are typically needed?
The number of sessions varies depending on the tumor size and response, but multiple sessions may be required over time.
What are the side effects of TACE Therapy?
Common side effects include fever, nausea, fatigue, and abdominal pain, which usually resolve within a few days after treatment.
Is TACE safe for patients with poor liver function?
TACE is generally not recommended for patients with poor liver function, as the procedure can further affect liver health.
How long does it take to recover after a TACE procedure?
Most patients can resume normal activities within a week, although full recovery may take up to 2 weeks.
Can TACE be combined with other cancer treatments?
Yes, TACE is often combined with systemic treatments like chemotherapy or targeted therapies for better outcomes.
Discover the Best Oncologists and Cancer Hospitals in India
When it comes to cancer treatment, finding the right specialist and hospital can make a significant difference in the outcome. In this blog, we have compiled a list of the top oncologists and cancer hospitals across major cities in India, ensuring that you have access to the best care available.
Top Oncologists in Major Cities
For those seeking expert oncologists, we have identified the best specialists in key cities:
Leading Cancer Hospitals
In addition to finding the right specialist, choosing the right hospital is crucial for comprehensive cancer care. Here are the top hospitals in major cities:
Conclusion
Finding the right oncologist and hospital is the first step in your cancer treatment journey. Explore the links above to learn more about the top specialists and hospitals in your area.
Related Resources
At ArogyaJivan, we strive to provide you with the most accurate and up-to-date information to help you make informed decisions about your healthcare. Whether you are searching for the Best Doctors in India or the Top 5 Doctors in India, our resources are tailored to guide you through your medical journey. Additionally, our comprehensive guides on the Best Hospitals in India and the Top 5 Hospitals in India will assist you in choosing the right healthcare facility for your needs. Explore these resources to ensure you receive the best possible care.